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HomeProduct name list2-[(4-NITROPHENYL)AMINO]ETHANOL

2-[(4-NITROPHENYL)AMINO]ETHANOL

2-[(4-NITROPHENYL)AMINO]ETHANOL Structural

What is 2-[(4-NITROPHENYL)AMINO]ETHANOL?

The Uses of 2-[(4-NITROPHENYL)AMINO]ETHANOL

2-[(4-nitrophenyl)amino]ethanol is used to prepare phenylpurinediamine derivatives as a class of reversible kinase inhibitors targeting both EGFR-activating and resistance mutations of lung cancer. It is also used to synthesize benzannulated N-heterocycles via palladium-catalyzed domino intermolecular alkylation/intramolecular amination of functionalized aryl iodides and bromoalkylamines.

Synthesis Reference(s)

Synthesis, p. 606, 1976 DOI: 10.1055/s-1976-24135

Properties of 2-[(4-NITROPHENYL)AMINO]ETHANOL

Melting point: 111-111.5 °C
Boiling point: 389.5±22.0 °C(Predicted)
Density  1.352±0.06 g/cm3(Predicted)
pka 14.57±0.10(Predicted)
color  Yellow

Safety information for 2-[(4-NITROPHENYL)AMINO]ETHANOL

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H317:Sensitisation, Skin
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for 2-[(4-NITROPHENYL)AMINO]ETHANOL

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