2-[(4-NITROPHENYL)AMINO]ETHANOL
- CAS NO.：1965-54-4
- Empirical Formula: C8H10N2O3
- Molecular Weight: 182.18
- MDL number: MFCD00156330
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-04-23 13:52:06
![2-[(4-NITROPHENYL)AMINO]ETHANOL Structural](https://img.chemicalbook.in/CAS/GIF/1965-54-4.gif)
What is 2-[(4-NITROPHENYL)AMINO]ETHANOL?
The Uses of 2-[(4-NITROPHENYL)AMINO]ETHANOL
2-[(4-nitrophenyl)amino]ethanol is used to prepare phenylpurinediamine derivatives as a class of reversible kinase inhibitors targeting both EGFR-activating and resistance mutations of lung cancer. It is also used to synthesize benzannulated N-heterocycles via palladium-catalyzed domino intermolecular alkylation/intramolecular amination of functionalized aryl iodides and bromoalkylamines.
Synthesis Reference(s)
Synthesis, p. 606, 1976 DOI: 10.1055/s-1976-24135
Properties of 2-[(4-NITROPHENYL)AMINO]ETHANOL
| Melting point: | 111-111.5 °C |
| Boiling point: | 389.5±22.0 °C(Predicted) |
| Density | 1.352±0.06 g/cm3(Predicted) |
| pka | 14.57±0.10(Predicted) |
| color | Yellow |
Safety information for 2-[(4-NITROPHENYL)AMINO]ETHANOL
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H317:Sensitisation, Skin |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 2-[(4-NITROPHENYL)AMINO]ETHANOL
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product: 1965-54-4 2 - ( ( 4 - nitrophenyl ) amino ) ethan - 1 - ol 98%
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