2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
Synonym(s):[2-(2,6-Dichloro-4-hydroxy-phenylamino)phenyl]acetic acid;4′-Hydroxy Diclofenac
- CAS NO.:64118-84-9
- Empirical Formula: C14H11Cl2NO3
- Molecular Weight: 312.15
- MDL number: MFCD01671980
- EINECS: 626-698-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID?
Description
4-hydroxy Diclofenac is a CYP2C9 metabolite of the NSAID diclofenac . By inhibiting COX and subsequently suppressing PGE2 synthesis, it demonstrates anti-inflammatory and analgesic properties.
Chemical properties
Light Violet Solid
The Uses of 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
A metabolite of Diclofenac, a nonsteroidal anti-inflammatory compound and cyclooxygenase (COX) inhibitor
The Uses of 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
A metabolite of Diclofenac, a nonsteroidal inflammatory compound and cyclooxygenase (COX) inhibitor.
The Uses of 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
A Cytochrome P450 2C9 (CYP2C9) metabolite of diclofenac
What are the applications of Application
4′-Hydroxy Diclofenac is a Cox-2 inhibitor and an active CYP2C9 metabolite of the NSAID diclofenac.
Definition
ChEBI: An monocarboxylic acid that is the 4'-hydroxylated metabolite of diclofenac.
General Description
4′-Hydroxydiclofenac is one of the metabolites of diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) used in human and veterinary medicine.
Properties of 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
Melting point: | 178-185°C dec. |
Boiling point: | 432.7±45.0 °C(Predicted) |
Density | 1.520±0.06 g/cm3(Predicted) |
Flash point: | 2℃ |
storage temp. | -20°C |
solubility | Soluble in DMSO, ethanol or methanol |
form | neat |
pka | 4.17±0.10(Predicted) |
form | Solid |
color | White to off-white |
BRN | 4198042 |
Stability: | Light Sensitive |
Safety information for 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Environment GHS09 |
GHS Hazard Statements |
H301:Acute toxicity,oral H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H410:Hazardous to the aquatic environment, long-term hazard |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 2-[((2',6'-DICHLORO-4'-HYDROXY)PHENYL)AMINO]BENZENEACETIC ACID
Abamectin manufacturer
Varanous Labs Pvt Ltd
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