2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol

Synonym(s):(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol;(1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol solution;t-Octylphenoxypolyethoxyethanol;Polyethylene Glycol- p-isooctylphenyl Ether, Octylphenoxypolyethoxyethanol;Polyethylene glycol tert-octylphenyl ether

CAS NO.：9036-19-5
Empirical Formula: C18H30O3
Molecular Weight: 294.43
MDL number: MFCD00134077
EINECS: 999-999-2
SAFETY DATA SHEET (SDS)
Update Date: 2024-12-18 14:15:30

2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol Structural

What is 2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol?

The Uses of 2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol

Triton^? X-100 has been used:

In immunohistochemistry for staining the Flat-mount retinas
Along with ice-cold PBS (phosphate buffered saline) in suspension of cells for cell DNA analysis and Annexin V assay
To permeabilise cells during Immunofluorescent microscopic studies
As a positive control in LDH assay to determine the cell membrane integrity
For estimating the lipase activity in postheparin plasma by using modified Belfrage and Vaughan radioenzymatic procedure
For the preparation of outer membrane protein exctract
As a component of extraction buffer along with tris-HCl, NaCl, CaCl₂, ZnCl₂, Brij 35 for homogenization of mice lung cells
In the treatment of tissue sections for Immunofluorescence labeling

The Uses of 2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol

0·3% Triton^? X-100 in TBS has been used for permeabilization of retinas before immunostaining. 0.5% Triton X-100 has been used for astrocyte cell lysis.

The Uses of 2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol

Triton^?-X has been used:

In the permeabilization of cells for immunofluorescence staining
As a component of lysis buffer in western blot analysis
As a component of Tris-buffered saline for the preparation of cell sections in Immunogold labelling for electron microscope

General Description

Octophenolpoly(ethyleneglycolether)_n
Especially used for purification in membrane research
Triton X-100 is a water soluble, non-ionic surfactant. It exhibits a strong hydrogen bonding with water molecule in temperature dependent manner. It has a wide application area such as in isolation and solubilization of protein, DNA extraction and emulsification.

Biochem/physiol Actions

Widely used non-ionic surfactant for recovery of membrane components under mild non-denaturing conditions.

Safety Profile

Moderately toxic by ingestion.When heated to decomposition it emits acrid smoke andirritating fumes.

Safety Profile

Moderately toxic by ingestion. Aneye irritant. When heated to decomposition it emits acridsmoke and irritating fumes.

Properties of 2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol

Melting point:	0.05°C
Boiling point:	586.77°C (rough estimate)
Density	1.06 g/mL at 20 °C
vapor pressure	<0.01 hPa (20 °C)
refractive index	n20/D 1.492
Flash point:	>230 °F
storage temp.	Store at +5°C to +30°C.
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly), Water (Slightly)
form	Liquid
color	Yellow
PH	5.0-8.0 (10g/l, H2O, 20℃)
Water Solubility	Miscible with water.
Merck	13,6793
BRN	2315025
Dielectric constant	9.8（29.0℃）
CAS DataBase Reference	9036-19-5(CAS DataBase Reference)
EPA Substance Registry System	Polyethylene glycol mono(1,1,3,3-tetramethylbutyl)phenyl ether (9036-19-5)

Safety information for 2-(2-[4-(1,1,3,3-Tetramethylbutyl)phenoxy]ethoxy)ethanol

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Environment GHS09
GHS Hazard Statements	H315:Skin corrosion/irritation H318:Serious eye damage/eye irritation H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water.