(1S)-(+)-(Camphorylsulfonyl)oxaziridine

Synonym(s):(1S)-(+)-(Camphorylsulfonyl)oxaziridine;(1S)-(+)-2,N-Epoxy-exo-10,2-bornanesultam

(1S)-(+)-(Camphorylsulfonyl)oxaziridine is white crystall powder

(1S)-(+)-(Camphorylsulfonyl)oxaziridine is a useful synthetic intermediate. Used for asymmetric hydroxylation

(1S)-(+)-(10-Camphorsulfonyl)oxaziridine can be used:

To convert prochiral ketone enolates into optically active α-hydroxy ketones via enantioselective asymmetric oxidation.
In the synthesis of thymidine oligonucleotides connected through pyrophosphates.
In the asymmetric synthesis of proton pump inhibitors like (R)-Rabeprazole sodium and (R)-Lansoprazole sodium from the corresponding DBU salt of prochiral sulfide.
In the preparation of phosphonoacetate and thiophosphonoacetate oligodeoxynucleotides by oxidizing the corresponding phosphinoacetate.

(1S)-(+)-(10-Camphorsulfonyl)oxaziridine is a useful Camphor derivative

Melting point:	172-174 °C(lit.)
Boiling point:	317.6±25.0 °C(Predicted)
alpha	45 º (c=2, chloroform)
Density	1.2486 (rough estimate)
refractive index	1.5060 (estimate)
storage temp.	2-8°C
solubility	Chloroform (Sparingly), Methanol (Slightly)
form	Crystals or Crystalline Powder
pka	-11.75±0.40(Predicted)
color	White
optical activity	[α]28/D +45°, c = 2 in chloroform
BRN	6274370
CAS DataBase Reference	104322-63-6(CAS DataBase Reference)

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection.