tert-Butyl 5-((2-(3-hydroxyphenyl)quinazolin-4-yl)amino)-1H-indazole-1-carboxylate

CAS NO.：911417-26-0
Empirical Formula: C26H23N5O3
Molecular Weight: 453.49
MDL number: MFCD28347542
SAFETY DATA SHEET (SDS)
Update Date: 2023-11-15 11:20:06

What is tert-Butyl 5-((2-(3-hydroxyphenyl)quinazolin-4-yl)amino)-1H-indazole-1-carboxylate?

The Uses of tert-Butyl 5-((2-(3-hydroxyphenyl)quinazolin-4-yl)amino)-1H-indazole-1-carboxylate

1H-Indazole-1-carboxylic acid, 5-[[2-(3-hydroxyphenyl)-4-quinazolinyl]aMino]-, 1,1-diMethylethyl ester is a valuable organic compound that could used to synthesize tert-Butyl 5-(2-(3-(2-tert-butoxy-2-oxoethoxy)phenyl)quinazolin-4-ylamino)-lH- indazole-l-carboxylate and tert-butyl 5-(2-(3-(2-(isopropylamino)-2-oxoethoxy)-phenyl)quinazolin-4- ylamino)-lH-indazole-l-carboxylate.

Synthesis

To a solution of give tert-butyl 5-(2-(3-acetoxyphenyl)quinazolin-4-ylamino)-lH- indazole-l-carboxylate (5.85 g, 11.8 mmole) in anhydrous MeOH (400 mL) was added 28 % (wt/v) NH4OH solution (6.50 mL). The reaction mixture was stirred at ambient temperature for 48 h. The crude product was filtered and washed with ether followed by hexane and dried under high vacuum overnight to give tert-Butyl 5-((2-(3-hydroxyphenyl)quinazolin-4-yl)amino)-1H-indazole-1-carboxylate (1H-Indazole-1-carboxylic acid, 5-[[2-(3-hydroxyphenyl)-4-quinazolinyl]aMino]-, 1,1-diMethylethyl ester).

Properties of tert-Butyl 5-((2-(3-hydroxyphenyl)quinazolin-4-yl)amino)-1H-indazole-1-carboxylate

Boiling point:	602.7±65.0 °C(Predicted)
Density	1.32±0.1 g/cm3(Predicted)
pka	9.20±0.10(Predicted)

Safety information for tert-Butyl 5-((2-(3-hydroxyphenyl)quinazolin-4-yl)amino)-1H-indazole-1-carboxylate

Computed Descriptors for tert-Butyl 5-((2-(3-hydroxyphenyl)quinazolin-4-yl)amino)-1H-indazole-1-carboxylate

Abamectin manufacturer

VGS SYNTHESIS PRIVATE LIMITED

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product: 911417-26-0 1,1-Dimethylethyl 5-[[2-(3-hydroxyphenyl)-4-quinazolinyl]amino]-1H-indazole-1-carboxylate 98%

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