1,4,8,11-TETRAAZACYCLOTETRADECANE

Chemical properties

white fluffy needle-like crystalline powder

The Uses of 1,4,8,11-TETRAAZACYCLOTETRADECANE

1,4,8,11-Tetraazacyclotetradecane is macrocyclic ligand that is used as an antioxidant in rubber and has been shown to suppress oxidation catalyzed by some metal ions.

The Uses of 1,4,8,11-TETRAAZACYCLOTETRADECANE

Reagent used in the preparation of Plerixafor derivatives.

The Uses of 1,4,8,11-TETRAAZACYCLOTETRADECANE

1,4,8,11-Tetraazacyclotetradecane is used in the synthesis of molecules with electroactive cavities. It acts as a nitrogen crown ether analogue and as an antioxidant in rubber. It is also used in the preparation of plerixafor derivatives.

What are the applications of Application

1,4,8,11-Tetraazacyclotetradecane is a Nitrogen crown ether analogue

Definition

ChEBI: 1,4,8,11-tetraazacyclotetradecane is a saturated organic heteromonocyclic parent, a crown amine and an azacycloalkane. It derives from a hydride of a cyclotetradecane.

General Description

1,4,8,11-Tetraazacyclotetradecane is an azamacrocycle that forms more stable metal complexes as compared to open chain ligands.

Purification Methods

Purify cyclam by recrystallisation from dioxane (white needles), and it sublimes above 120o. It has been distilled, b 132-140o/4-8mm. It forms complexes with metals and gives a sparingly soluble nitrate salt, m 205o(dec), which crystallises from H2O and is dried at 150o. [UV: Bosnich et al. Inorg Chem 4 1102 1963, van Alphen Recl Trav Chim Pays-Bas 56 343 1937, Beilstein 26 III/IV 1647.]