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HomeProduct name list1,3-DIOXANE

1,3-DIOXANE

Synonym(s):Formaldehyde trimethylene acetal

  • CAS NO.:505-22-6
  • Empirical Formula: C4H8O2
  • Molecular Weight: 88.11
  • MDL number: MFCD00006566
  • EINECS: 208-005-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-08-21 22:41:43
1,3-DIOXANE Structural

What is 1,3-DIOXANE?

Chemical properties

colourless liquid

The Uses of 1,3-DIOXANE

1,3-Dioxane has been employed as solvent in the synthesis of 8- and 9-membered dioxazocines and dioxazonines.

Definition

ChEBI: 1,3-dioxane is a dioxane and a cyclic acetal.

Preparation

1,3-dioxane is prepared by the reaction of formaldehyde and 1,3-propanediol in the presence of Br?nsted or Lewis acid catalysts.

General Description

Clear colorless liquid.

Air & Water Reactions

Highly flammable. Can form dangerous peroxides when exposed to air. Water soluble.

Reactivity Profile

1,3-DIOXANE is sensitive to heat. 1,3-DIOXANE can react with oxidizers.

Health Hazard

ACUTE/CHRONIC HAZARDS: When heated to decomposition 1,3-DIOXANE emits acrid smoke and fumes.

Fire Hazard

1,3-DIOXANE is flammable.

Purification Methods

Dry the dioxane with sodium and fractionally distil it. [Beilstein 19/1 V 11.]

Properties of 1,3-DIOXANE

Melting point: -45 °C (lit.)
Boiling point: 105-106 °C (lit.)
Density  1.032 g/mL at 25 °C (lit.)
refractive index  n20/D 1.418(lit.)
Flash point: 59 °F
storage temp.  Flammables area
form  clear liquid
color  Colorless to Almost colorless
Water Solubility  Fully miscible in water.
BRN  102532
Stability: Stable. Flammable. Incompatible with oxidizing agents. May form explosive peroxides in contact with the air - store under inert gas.
EPA Substance Registry System 1,3-Dioxane (505-22-6)

Safety information for 1,3-DIOXANE

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H225:Flammable liquids
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P280:Wear protective gloves/protective clothing/eye protection/face protection.

Computed Descriptors for 1,3-DIOXANE

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