1,1,1,3,5,5,5-Heptamethyltrisiloxane

Synonym(s):1,1,1,3,5,5,5-Heptamethyltrisiloxane

CAS NO.：1873-88-7
Empirical Formula: C7H22O2Si3
Molecular Weight: 222.5
MDL number: MFCD00048000
EINECS: 217-496-1
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-28 16:48:35

1,1,1,3,5,5,5-Heptamethyltrisiloxane Structural

What is 1,1,1,3,5,5,5-Heptamethyltrisiloxane?

Description

Bis (trimethylsiloxy) methylsilane acts as an important raw material and intermediate used in organic synthesis, pharmaceutical and dyestuff. For example, it can be used for the platinum-catalyzed aromatic C-H silylation of arenes. It can also be used for the silylation of aryl iodides.

Chemical properties

colourless liquid

The Uses of 1,1,1,3,5,5,5-Heptamethyltrisiloxane

1,1,1,3,5,5,5-Heptamethyltrisiloxane is a Basic material for synthetic polyalkyleneoxide modified heptamethyltrisiloxane which is a kind of specific structure surfactant for pesticide additives, coating additives, etc.

The Uses of 1,1,1,3,5,5,5-Heptamethyltrisiloxane

Bis(trimethylsiloxy)methylsilane is an important raw material and intermediate used in organic synthesis, pharmaceutical and dyestuff.

The Uses of 1,1,1,3,5,5,5-Heptamethyltrisiloxane

1,1,1,3,5,5,5-Heptamethyltrisiloxane can be used for the aromatic C-H silylation of arenes in the presence of a platinum complex catalyst.
It can also be used as a reagent to synthesize:

3-Octyl-1,1,1,3,5,5,5-heptamethyltrisiloxane, an agricultural adjuvant and sensory performance enhancer used in cosmetic formulations.
Isoindigo-based conjugated polymer with siloxane-terminated solubilizing group.
Monosiloxy esters with a variety of acids.

Flammability and Explosibility

Flammable

References

https://www.alfa.com/zh-cn/catalog/H60586/
Murata, Miki, et al. "Silylation of Aryl Iodides with 1,1,1,3,5,5,5 -Heptamethyltrisiloxane Catalyzed by Transition-Metal Complexes." Synlett 2007.09(2007):1387-1390.
Murata, Miki, et al. "Platinum-Catalyzed Aromatic C—H Silylation of Arenes with 1,1,1,3,5,5,5-Heptamethyltrisiloxane." Cheminform38.50 (2007):no-no.

Properties of 1,1,1,3,5,5,5-Heptamethyltrisiloxane

Melting point:	<0°C
Boiling point:	142 °C (lit.)
Density	0.819 g/mL at 25 °C (lit.)
vapor pressure	8.5hPa at 25℃
refractive index	n20/D 1.382(lit.)
Flash point:	82 °F
storage temp.	15-25°C
solubility	Chloroform (Soluble), Methanol (Slightly)
form	clear liquid
Specific Gravity	0.8136
color	Colorless to Almost colorless
Water Solubility	Miscible with acetone, ethanol, diethyl ether. Insoluble in water.
Hydrolytic Sensitivity	3: reacts with aqueous base
BRN	1748455
Stability:	Stable. Flammable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	1873-88-7(CAS DataBase Reference)
NIST Chemistry Reference	Trisiloxane, 1,1,1,3,5,5,5-heptamethyl-,(1873-88-7)
EPA Substance Registry System	Trisiloxane, 1,1,1,3,5,5,5-heptamethyl- (1873-88-7)

Safety information for 1,1,1,3,5,5,5-Heptamethyltrisiloxane

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H225:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.