1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE

Synonym(s):DiI

CAS NO.：41085-99-8
Empirical Formula: C59H97ClN2O4
Molecular Weight: 933.87
MDL number: MFCD00142354
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-31 20:01:59

1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE Structural

What is 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE?

The Uses of 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE

1,1'-Di-n-octadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate is used primarily for optical recordings of membrane voltage and for studies of membrane fluidity. Retrograde stain for neurons; provides intense, long-lasting staining of live neurons in vivo and in vitro.

The Uses of 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE

1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine per chlorate is a lipophilic dye used to record membrane voltage for fluidity studies. This retrograde stain is useful in staining neurons?in vitro?and?in vivo?because the stain is relatively nontoxic to cell bodies and the dye is retained in neurons. In addition, 1,1'-Dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine per chlorate is an ideal retrograde and anterograde tracer to label the processes as well as the cell bodies of cultured neurons.

The Uses of 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate has been used in fluorescent labelling of mesenchymal stem cells (MSCs)?and cerebral cortex. It has also been used in electromyogram (EMG) to determine awake and anesthetized states in mice.

What are the applications of Application

1,1′-Dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate is a dye used to record membrane voltage

General Description

DiI is a Dye Aye, a chemical with CAS number 41085-99-8. It is a fluorescent lipophilic cationic indocarbocyanine dye, which is usually made as a perchlorate salt. Mostly used for scientific staining purposes, such as single molecule imaging, fate mapping and neuronal tracing (as DiI is retained in the lipid bilayers).

Biochem/physiol Actions

Lipophilic carbocyanine dye used primarily for optical recordings of membrane voltage and for studies of membrane fluidity. Retrograde stain for neurons; provides intense, long-lasting staining of live neurons in vivo and in vitro.

Properties of 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE

Melting point:	68 °C (dec.)(lit.)
storage temp.	2-8°C
solubility	DMF: soluble
form	crystals or powder
color	Burgundy to purples-violet
λmax	549 nm
BRN	8251870
Biological Applications	Detecting cell fusion,cell adhesion,cell migration,cell proliferation; membrane fusion assay; exocytosis and/or endocytosis assay
CAS DataBase Reference	41085-99-8

Safety information for 1,1'-DIOCTADECYL-3,3,3',3'-TETRAMETHYLINDOCARBOCYANINE PERCHLORATE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.