1,1-DIMETHOXYCYCLOHEXANE

Synonym(s):1,1-Dimethoxycyclohexane

CAS NO.：933-40-4
Empirical Formula: C8H16O2
Molecular Weight: 144.21
MDL number: MFCD00043714
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-08 17:06:37

What is 1,1-DIMETHOXYCYCLOHEXANE?

The Uses of 1,1-DIMETHOXYCYCLOHEXANE

1,1-Dimethoxycyclohexane is a useful research chemical used in the preparation of N-??substituted valiolamine derivatives as potential oral antidiabetic agents.

Synthesis Reference(s)

Canadian Journal of Chemistry, 61, p. 366, 1983 DOI: 10.1139/v83-065
Tetrahedron Letters, 30, p. 6151, 1989 DOI: 10.1016/S0040-4039(01)93328-3

General Description

Cyclohexanone dimethyl ketal reacts with trimethylsilane in the presence of trimethylsilyl triflate to form the corresponding ether. It can also undergo allylation and propargylation in the presence of indium to form the corresponding homoallylic or homopropargylic alcohol, respectively.

Properties of 1,1-DIMETHOXYCYCLOHEXANE

Boiling point:	83 °C/50 mmHg (lit.)
Density	0.948 g/mL at 25 °C (lit.)
refractive index	n20/D 1.439(lit.)
Flash point:	50°C
solubility	Chloroform (Soluble), Ethyl Acetate (Slightly)
form	clear liquid
color	Colorless to Yellow
CAS DataBase Reference	933-40-4(CAS DataBase Reference)

Safety information for 1,1-DIMETHOXYCYCLOHEXANE

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02
GHS Hazard Statements	H226:Flammable liquids
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P243:Take precautionary measures against static discharge.