11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride
- CAS NO.：111974-74-4
- Empirical Formula: C17H18ClN3S
- Molecular Weight: 331.86
- MDL number: MFCD08703302
- EINECS: 1312995-182-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-03-22 11:53:02
![11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride Structural Picture](https://img.chemicalbook.in/CAS/GIF/111974-74-4.gif)
What is 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride?
Description
Norquetiapine 2HCl (111974-74-4) is a pharmacologically active metabolite of quetiapine (Seroquel).1? Exhibits distinct pharmacological activity from quetiapine and plays an important role in its antidepressant activity.2? Activates ERK1/2 and induces release of BDNF in C6 glioma cells which may contribute to the antidepressant properties of quetiapine.3?Inhibits the norepinephrine transporter which may contribute to the antipsychotic activity of quetiapine.4
The Uses of 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride
11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride is a metabolite of Quetiapine, a Benzothiazepine with mixed serotonin and dopamine receptor antagonistic properties used as an antipsychotic
What are the applications of Application
11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride is a metabolite of Quetiapine
Properties of 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride
| Melting point: | 180-184°C |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | Soluble in DMSO, Methanol, Distilled Water |
| form | solid |
| color | Off-white |
Safety information for 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06 |
| GHS Hazard Statements |
H413:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P273:Avoid release to the environment. |
Computed Descriptors for 11-(1-Piperazinyl)-dibenzo[b,f][1,4]thiazepine dihydrochloride
Abamectin manufacturer
AnalyticsStanza Inc
1Y
Phone:+91-7032031309
Whatsapp: +91 7032031309
product: 111974-74-4 Nitroso aryl piperazine quetiapine /N-Nitroso quetiapine imp 98.42
KARPSCHEM LABORATORIES PVT. LTD.
1Y
Phone:+91 7249203006;+91-9371639228
Whatsapp: +91 7249203006
product: 111974-74-4 96%
R L Fine Chem Pvt. Ltd
1Y
Phone:+91-8042488999
product: 11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride 98%
Aarti Industries Limited (AIL)
1Y
Phone:+91-9920899935
Whatsapp: +91 9920899935
product: 11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride 111974-74-4 98%
Lakshmi Farmachem
1Y
Phone:+91-9550886476
Whatsapp: +91-9550886476
product: 11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride 98%
Aruvi Labs
1Y
Phone:+91-8056181939
Whatsapp: +91-8056181939
product: 11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride 98%
Aventus Labs
1Y
Phone:+91-9324342304
Whatsapp: +91-9324342304
product: 11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride 111974-74-4 98%
Saburi Life Sciences
1Y
Phone:+91-9177339666
Whatsapp: +91 9177339666
product: 111974-74-4 11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride 98%
New Products
3-N-BOC-(S)-AMINO BUTYRONITRILE 4-Piperidinopiperidine 2-Methyl-4-nitrobenzoic acid 2-(4-bromophenyl)-2-methylpropanoic acid 4-Acetyl-2-methylbenzoicacid Acetyl-meldrum's acid Ethyl-4-Pyrazole carboxylate 2,6 Di acetylpyridine 2,6-Pyridinedimethanol 5,7-Dichloro-3H-Imidazo[4,5-B]Pyridine 5-Bromo-2-Methoxy-4-Methyl-3-Nitropyridine 2-Fluoro-5-Iodopyridine 2-Fluoro-5-Methylpyridine 2-Chloro-3-Bromo-5-Amiopyridine METHYL-4-(BUTYRYLAMINO)3-METHYL-5-NITROBENZOATE TRANS-CYCLOBUTANE-1,2- DICARBOXYLIC ACID 5-Nitro indazole R-(-)-5-(2-AMINO-PROPYL)-2-METHOXY-BENZENESULFONAMIDE 1,3-cyclohexanedione 4-Aminophenaethylalchol (S)-(+)-4-BENZYL-2-OXAZOLIDINONE 3-NITRO-5-ACETYL IMINODIBENZYL 1-HYDROXY-4-METHYL6-(2,4,4-TRI METHYL PHENYL)-2-PYRIDONE MONO ETHANOL AMINE(PIROCTONE OLAMINE) 4-FLUORO PHENYL MAGNESIUM BROMIDE 1.0 M IN THFRelated products of tetrahydrofuran
You may like
-
111974-74-4 Nitroso aryl piperazine quetiapine /N-Nitroso quetiapine imp 98.42View Details
111974-74-4 -
111974-74-4 96%View Details
111974-74-4 -
11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride 98%View Details
111974-74-4 -
11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride 111974-74-4 98%View Details
111974-74-4 -
11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride 98%View Details -
11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride 98%View Details
111974-74-4 -
11-Piperazinodibenzo[b,f][1,4]thiazepine dihydrochloride 111974-74-4 98%View Details
111974-74-4 -
111974-74-4 98%View Details
111974-74-4
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.