1-Phenyl-2-pyrrolidinone
- CAS NO.:4641-57-0
- Empirical Formula: C10H11NO
- Molecular Weight: 161.2
- MDL number: MFCD00003192
- EINECS: 225-069-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-26 11:58:42
What is 1-Phenyl-2-pyrrolidinone?
Chemical properties
Light Beige Solid
The Uses of 1-Phenyl-2-pyrrolidinone
A novel derivative of 1-phenyl-2-pyrrolidinone, blebbistatin, inhibits non-muscle myocin II activity with high specificity.
What are the applications of Application
1-Phenyl-2-pyrrolidinone is a novel derivative of 1-phenyl-2-pyrrolidinone
Synthesis Reference(s)
Journal of the American Chemical Society, 77, p. 4079, 1955 DOI: 10.1021/ja01620a034
Synthesis, p. 856, 1985
Properties of 1-Phenyl-2-pyrrolidinone
Melting point: | 67-69 °C (lit.) |
Boiling point: | 123 °C/0.2 mmHg (lit.) |
Density | 1.0840 (rough estimate) |
refractive index | 1.5200 (estimate) |
Flash point: | 123°C/0.2mm |
storage temp. | Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Ethyl Acetate, Methanol (Slightly) |
form | Solid |
pka | 0.54±0.20(Predicted) |
color | Light Beige |
Water Solubility | Soluble in chloroform and ethyl Acetate. Insoluble in water. |
BRN | 130685 |
CAS DataBase Reference | 4641-57-0(CAS DataBase Reference) |
NIST Chemistry Reference | 2-Pyrrolidinone, 1-phenyl-(4641-57-0) |
Safety information for 1-Phenyl-2-pyrrolidinone
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-Phenyl-2-pyrrolidinone
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 2-aminopropyl benzoate hydrochloride 1-(4-(aminomethyl)benzyl)urea hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
N-(3-(TRIFLUOROMETHYL)PHENYL)SUCCINIMIDE
1-(2-aminophenyl)pyrrolidine-2,5-dione
1-(2,4-DIFLUOROPHENYL)DIHYDRO-1H-PYRROLE-2,5-DIONE
N-(4-BROMOPHENYL)SUCCINIMIDE
4-(1,3-DIOXO-1,3-DIHYDRO-2H-INDEN-2-YLIDEN)-2-PHENYL-6-(2-PYRIDINYL)TETRAHYDROPYRROLO[3,4-C]PYRROLE-1,3(2H,3AH)-DIONE
AURORA 15227
2-(2,5-DIOXO-1-PYRROLIDINYL)BENZENECARBOXYLIC ACID
1-(4-CHLOROPHENYL)-2,5-PYRROLIDINEDIONE
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