1-O-HEXADECYL-2-O-ACETYL-SN-GLYCEROL
Synonym(s):1-O-hexadecyl-2-acetyl-sn-glycerol (HAG)
- CAS NO.:77133-35-8
- Empirical Formula: C21H42O4
- Molecular Weight: 358.56
- MDL number: MFCD00065893
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:42
What is 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCEROL?
The Uses of 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCEROL
C16-02:0 DG or 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG) may be used to prevent 1-O-acyl-NAS formation.
The Uses of 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCEROL
C16-02:0 DG or 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG) may be used to inhibit the formation of 1-O-acyl-NAS.
What are the applications of Application
1-O-Hexadecyl-2-O-acetyl-sn-glycerol is an inhibitor of protein kinase C activation
Definition
ChEBI: 1-O-palmityl-2-acetyl-sn-glycerol is a 1-alkyl-2-acetylglycerol in which the 1-alkyl group is specified as palmityl (hexadecyl). It is a 1-alkyl-2-acetylglycerol and a 1-alkyl-2-acetyl-sn-glycerol. It is functionally related to an acetic acid.
General Description
C16-02:0 DG, also called as 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG), is an alkylacylglycerol and a bioactive lipid. Structurally, HAG contains primary alcohol group at the C3 position.
Biochem/physiol Actions
C16-02:0 DG or 1-O-hexadecyl-2-acetyl-sn-glycerol (HAG) is a diacylglycerol (DAG) antagonist with a potential to inhibit protein kinase C (PKC) activity. It also has an ability to inhibit growth of human promyelocytic leukemia cell line HL-60. HAG serves as a precursor in the biosynthesis of platelet-activating factor.
Properties of 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCEROL
storage temp. | -20°C |
solubility | DMSO: 10 mg/ml; Ethanol: Miscible; PBS (pH 7.2): ~150 μg/ml |
form | Waxy solid. |
Safety information for 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCEROL
Computed Descriptors for 1-O-HEXADECYL-2-O-ACETYL-SN-GLYCEROL
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