1-CHLORO-4-IODOBUTANE

CAS NO.：10297-05-9
Empirical Formula: C4H8ClI
Molecular Weight: 218.46
MDL number: MFCD00039415
EINECS: 233-669-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-07-24 18:26:40

What is 1-CHLORO-4-IODOBUTANE?

Chemical properties

clear yellow to brown liquid

The Uses of 1-CHLORO-4-IODOBUTANE

1-Chloro-4-iodobutane acts as a reagent in the synthesis of alkyl chromones/quinolones via cyclization/alkylation of enaminones and as an intermediate in many pharmaceutical synthesis.

The Uses of 1-CHLORO-4-IODOBUTANE

1-Chloro-4-iodobutane may be used in the following studies:

Preparation of 6-hendecenoic acid.
Catalytic asymmetric synthesis of levobupivacaine.
Synthesis of alkaloids such as deoxyvasicinone, mackinazolinone.

Definition

ChEBI: 1-Chloro-4-iodobutane is an organoiodine compound.

General Description

1-Chloro-4-iodobutane is a halogenated hydrocarbon. It is an α,ω-dihaloalkane and undergoes electrogenerated Nickel(I) salen (N,N′-bis(salicylidene)ethylenediamine) catalyzed reduction to afford 1,8-dichlorooctane. Electrochemical reduction of 1-chloro-4-iodobutane at glassy carbon cathode has been investigated by cyclic voltammetry and controlled-potential electrolysis.

Properties of 1-CHLORO-4-IODOBUTANE

Melting point:	93 °C
Boiling point:	88-89 °C/19 mmHg (lit.)
Density	1.785 g/mL at 25 °C (lit.)
refractive index	n20/D 1.54(lit.)
Flash point:	200 °F
storage temp.	2-8°C(protect from light)
solubility	Chloroform, Ethyl Acetate
form	Oil
color	Clear Colourless
Specific Gravity	1.785
Sensitive	Light Sensitive
BRN	1361365
CAS DataBase Reference	10297-05-9(CAS DataBase Reference)
EPA Substance Registry System	Butane, 1-chloro-4-iodo- (10297-05-9)

Safety information for 1-CHLORO-4-IODOBUTANE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.