1-Bromo-2,4,5-trifluorobenzene

CAS NO.：327-52-6
Empirical Formula: C6H2BrF3
Molecular Weight: 210.98
MDL number: MFCD00000306
EINECS: 206-318-8
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-20 17:10:30

What is 1-Bromo-2,4,5-trifluorobenzene?

Chemical properties

clear slightly yellow liquid

The Uses of 1-Bromo-2,4,5-trifluorobenzene

1-Bromo-2,4,5-trifluorobenzene is the intermediate of liquid crystals. The derivatives of this compound can be used as intermediates for the synthesis of qunolone antibacterial. It is employed in the synthesis of 3-ethenyl, 3-ethynyl, 3-aryl, and 3-cyclopropyl-2, 4, 5-trifluorobenzoic acids from 1-bromo-2, 4, 5-trifluorobenzene and 2, 4, 5-trifluoro-3-hydroxybenzoic acid.

The Uses of 1-Bromo-2,4,5-trifluorobenzene

Intermediates of Liquid Crystals

Definition

ChEBI: 1-Bromo-2,4,5-trifluorobenzene is an organofluorine compound.

General Description

1-Bromo-2,4,5-trifluorobenzene undergoes Br-Mg-exchange reaction with i-PrMgBr in THF to yield organomagnesium compound.

Properties of 1-Bromo-2,4,5-trifluorobenzene

Melting point:	−19 °C(lit.)
Boiling point:	144 °C(lit.)
Density	1.802 g/mL at 25 °C(lit.)
refractive index	n20/D 1.485(lit.)
Flash point:	132 °F
storage temp.	2-8°C
solubility	water: insoluble
form	clear liquid
Specific Gravity	1.81
color	Colorless to Light yellow to Light orange
Water Solubility	insoluble
BRN	1636588
CAS DataBase Reference	327-52-6(CAS DataBase Reference)
NIST Chemistry Reference	Benzene, 1-bromo-2,4,5-trifluoro-(327-52-6)

Safety information for 1-Bromo-2,4,5-trifluorobenzene

Signal word	Warning
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H226:Flammable liquids H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.