1-ACETYLINDOLINE
- CAS NO.:16078-30-1
- Empirical Formula: C10H11NO
- Molecular Weight: 161.2
- MDL number: MFCD00022908
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-12-30 16:20:48
What is 1-ACETYLINDOLINE?
The Uses of 1-ACETYLINDOLINE
• ;Reactant for preparation of triazolothiadiazepine dioxide derivatives1• ;Reactant for preparation of halo-substituted aromatic amides2• ;Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists3• ;Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents4• ;Reactant for regioselective ortho Suzuki-Miyaura coupling reaction5
The Uses of 1-ACETYLINDOLINE
1-(2,3-Dihydroindol-1-yl)ethanone is an intermediate used for preparation of triazolothiadiazepine dioxide derivatives, halo-substituted aromatic amides and [[(phenyl)piperazinyl]alkyl]indolyl]ethanone.
The Uses of 1-ACETYLINDOLINE
- Reactant for preparation of triazolothiadiazepine dioxide derivatives
- Reactant for preparation of halo-substituted aromatic amides
- Reactant for preparation of [[(phenyl)piperazinyl]alkyl]indolyl]ethanone and [[[(phenoxyethyl)piperazinyl]alkyl]indolyl]ethanone derivatives as α1-adrenoreceptor antagonists
- Reactant for synthesis of naphthalenedione derivatives as antimycobacterial agents
- Reactant for regioselective ortho Suzuki-Miyaura coupling reaction
Synthesis Reference(s)
Tetrahedron, 52, p. 7525, 1996 DOI: 10.1016/0040-4020(96)00266-9
Tetrahedron Letters, 24, p. 561, 1983 DOI: 10.1016/S0040-4039(00)81464-1
General Description
1-Acetylindoline, a substituted indole, is a tertiary amide having bulky N-groups. Its reduction to the corresponding amine, by reaction with silane in the presence of MoO2Cl2 (catalyst), has been reported.
Properties of 1-ACETYLINDOLINE
Melting point: | 102-104 °C(lit.) |
Boiling point: | 125-130 °C(Press: 1 Torr) |
Density | 1.144±0.06 g/cm3(Predicted) |
storage temp. | Sealed in dry,Room Temperature |
pka | 1.13±0.20(Predicted) |
CAS DataBase Reference | 16078-30-1(CAS DataBase Reference) |
Safety information for 1-ACETYLINDOLINE
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral H317:Sensitisation, Skin |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. |
Computed Descriptors for 1-ACETYLINDOLINE
Abamectin manufacturer
Syn Finechem Laboratories Pvt Ltd.
BASR Fine Chemicals Pvt. Ltd.
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