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HomeProduct name list1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

  • CAS NO.:62780-89-6
  • Empirical Formula: C10H11ClN2O
  • Molecular Weight: 210.66
  • MDL number: MFCD00044896
  • EINECS: 263-731-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2025-04-10 20:44:46
1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one Structural

What is 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one?

Chemical properties

1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one is WHITE TO SLIGHTLY BEIGE POWDER

The Uses of 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

1-(3-Chloropropyl)-1,3-dihydrobenzimidazol-2-one is a benzimidazole derivative used in the preparation of neuroleptic and antiallergic agents.

Flammability and Explosibility

Not classified

Effects

The active form of Phenylmethyl is 1-(3-chloropropyl)-1,3-dihydro-2H-benzimidazole-2-one (PCP). This drug inhibits bacterial growth by binding to the 50S ribosomal subunit and inhibiting protein synthesis. PCP has been shown to have a narrow spectrum of activity against most enteric bacteria and some protozoa.

Properties of 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

Melting point: 115-125 °C
Density  1.2798 (rough estimate)
vapor pressure  0.017Pa at 25℃
refractive index  1.5330 (estimate)
storage temp.  -20°C Freezer
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form  Powder
pka 12.11±0.30(Predicted)
color  White to slightly beige
Water Solubility  210 mg/L (20 ºC)
CAS DataBase Reference 62780-89-6(CAS DataBase Reference)

Safety information for 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
ghs
Environment
GHS09
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H317:Sensitisation, Skin
H318:Serious eye damage/eye irritation
H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P272:Contaminated work clothing should not be allowed out of the workplace.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P391:Collect spillage. Hazardous to the aquatic environment
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.
P501:Dispose of contents/container to..…

Computed Descriptors for 1-(3-Chloropropyl)-1,3-dihydro-2H-benzimidazol-2-one

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