1-(2-hydroxy-3-methoxy-phenyl)ethanone
- CAS NO.：703-98-0
- Empirical Formula: C9H10O3
- Molecular Weight: 166.17
- MDL number: MFCD12913657
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-09-20 16:43:00
What is 1-(2-hydroxy-3-methoxy-phenyl)ethanone?
The Uses of 1-(2-hydroxy-3-methoxy-phenyl)ethanone
2''-Hydroxy-3''-methoxyacetophenone, is an intermediate used for he synthesis of various chemical compounds. It can be used for the synthesis of 4''-Hydroxy-3-methoxyflavones with potent antipicornavirus activity.
Preparation
Preparation from 2,3-dimethoxybenzonitrile and methyl-magnesium iodide in refluxing ethyl ether (Grignard reaction) (75%).
Properties of 1-(2-hydroxy-3-methoxy-phenyl)ethanone
| Melting point: | 54 °C |
| Boiling point: | 247.2±20.0 °C(Predicted) |
| Density | 1.158±0.06 g/cm3(Predicted) |
| storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 10.17±0.10(Predicted) |
| color | Pale Yellow to Light Yellow |
Safety information for 1-(2-hydroxy-3-methoxy-phenyl)ethanone
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1-(2-hydroxy-3-methoxy-phenyl)ethanone
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product: 703-98-0 2'-Hydroxy-3'-methoxyacetophenone 99%
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