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HomeProduct name list1-(2-hydroxy-3-methoxy-phenyl)ethanone

1-(2-hydroxy-3-methoxy-phenyl)ethanone

1-(2-hydroxy-3-methoxy-phenyl)ethanone Structural

What is 1-(2-hydroxy-3-methoxy-phenyl)ethanone?

The Uses of 1-(2-hydroxy-3-methoxy-phenyl)ethanone

2''-Hydroxy-3''-methoxyacetophenone, is an intermediate used for he synthesis of various chemical compounds. It can be used for the synthesis of 4''-Hydroxy-3-methoxyflavones with potent antipicornavirus activity.

Preparation

Preparation from 2,3-dimethoxybenzonitrile and methyl-magnesium iodide in refluxing ethyl ether (Grignard reaction) (75%).

Properties of 1-(2-hydroxy-3-methoxy-phenyl)ethanone

Melting point: 54 °C
Boiling point: 247.2±20.0 °C(Predicted)
Density  1.158±0.06 g/cm3(Predicted)
storage temp.  under inert gas (nitrogen or Argon) at 2-8°C
solubility  Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form  Solid
pka 10.17±0.10(Predicted)
color  Pale Yellow to Light Yellow

Safety information for 1-(2-hydroxy-3-methoxy-phenyl)ethanone

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 1-(2-hydroxy-3-methoxy-phenyl)ethanone

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