(+/-)-trans-1,2-Diaminocyclohexane
Synonym(s):(±)-trans-1,2-Cyclohexanediamine
- CAS NO.:1121-22-8
- Empirical Formula: C6H14N2
- Molecular Weight: 114.19
- MDL number: MFCD00063747
- EINECS: 601-163-6
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-09-03 18:36:42
What is (+/-)-trans-1,2-Diaminocyclohexane?
Chemical properties
clear colorless to light yellow liquid
The Uses of (+/-)-trans-1,2-Diaminocyclohexane
(^+)-trans-1,2-Diaminocyclohexane is employed in the synthesis of macrocyclic [3+3] hexa Schiff base. It also plays an important role in the preparation of multidentate ligands, chiral auxiliaries and chiral stationary phases. Further, it is used to prepare [2+2] macrocyclization by reacting with aliphatic dialdehydes. In addition to this, it acts as a chiral ligand, which finds application in asymmetric catalysis.
The Uses of (+/-)-trans-1,2-Diaminocyclohexane
(±)-trans-1,2-Diaminocyclohexane was used in the synthesis of macrocyclic [3+3] hexa Schiff base. It was also employed in the synthesis of multidentate ligands, chiral auxiliaries and chiral stationary phases.
What are the applications of Application
(±)-trans-1,2-Diaminocyclohexane is a reagent used in the synthesis of multidentate ligands, chiral auxiliaries, and chiral stationary phases
General Description
(±)-trans-1,2-Diaminocyclohexane was condensed with aliphatic dialdehydes to form [3+3] or [2+2] macrocyclization products.
Purification Methods
Purify and store the diamine as for the cis-isomer above as it is a strong base and becomes yellow on storage. [Beilstein 13 IV 1.]
Properties of (+/-)-trans-1,2-Diaminocyclohexane
Melting point: | 14-15 °C(lit.) |
Boiling point: | 79-81 °C15 mm Hg(lit.) |
Density | 0.951 g/mL at 25 °C(lit.) |
vapor pressure | 0.4 mm Hg ( 20 °C) |
refractive index | n |
Flash point: | 156 °F |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | Chloroform (Slightly), Methanol (Slightly) |
pka | 9.94(at 20℃) |
form | Liquid |
color | Clear colorless to light yellow |
Water Solubility | Soluble |
Sensitive | Air Sensitive |
BRN | 506142 |
CAS DataBase Reference | 1121-22-8(CAS DataBase Reference) |
NIST Chemistry Reference | trans-1,2-Cyclohexanediamine(1121-22-8) |
EPA Substance Registry System | 1,2-Cyclohexanediamine, (1R,2R)-rel- (1121-22-8) |
Safety information for (+/-)-trans-1,2-Diaminocyclohexane
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 |
GHS Hazard Statements |
H314:Skin corrosion/irritation |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P363:Wash contaminated clothing before reuse. P301+P330+P331:IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (+/-)-trans-1,2-Diaminocyclohexane
InChIKey | SSJXIUAHEKJCMH-WDSKDSINSA-N |
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