(+/-)-BENZYLOXYCARBONYL-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER

Synonym(s):(±)-Methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphinyl) acetate;(±)-Trimethyl Z-α-phosphonoglycinate;(±)-Z-α-Phosphonoglycine trimethyl ester

CAS NO.：88568-95-0
Empirical Formula: C13H18NO7P
Molecular Weight: 331.26
MDL number: MFCD00043304
EINECS: 629-458-5
SAFETY DATA SHEET (SDS)
Update Date: 2024-02-28 13:12:49

(+/-)-BENZYLOXYCARBONYL-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER Structural

What is (+/-)-BENZYLOXYCARBONYL-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER?

Description

(+/-)-Benzyloxycarbonyl-alpha-phosphonoglycine trimethyl ester is an important organic compound with the appearance of white to off-white powder to crystals, melting point of 78.0~ 82.0 °C, soluble in methanol, irritating to the eyes and skin, store in a cool, dry place in a closed Keep away from strong oxidising agents. Keep away from strong oxidising agents. It is mainly used in chemical industry and experimental research.

Chemical properties

White crystalline powder

The Uses of (+/-)-BENZYLOXYCARBONYL-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER

Z-α-Phosphonoglycine is used in the synthesis of calcitonin gene-related peptide antagonists. Also used in the synthesis of dehydroamino acid esters for amino acid and peptide research.

The Uses of (+/-)-BENZYLOXYCARBONYL-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER

Starting material for the synthesis of (Z)-dehydroamino acids by Wittig-Horner reaction with aldehydes; the dehydroamino acids can be stereoselectively reduced to amino acids

What are the applications of Application

(±)-Z-α-Phosphonoglycine trimethyl ester is a starting material for the synthesis of (Z)-dehydroamino acids

Properties of (+/-)-BENZYLOXYCARBONYL-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER

Melting point:	77-80 °C(lit.)
Boiling point:	480.5±45.0 °C(Predicted)
Density	1.284±0.06 g/cm3(Predicted)
storage temp.	Keep in dark place,Sealed in dry,Room Temperature
solubility	Soluble in methanol.
form	Crystalline Powder
pka	9.42±0.46(Predicted)
color	White
BRN	5764460
CAS DataBase Reference	88568-95-0(CAS DataBase Reference)

Safety information for (+/-)-BENZYLOXYCARBONYL-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.