Lorlatinib

Melting point::

184-187°C

Boiling point::

675.0±55.0 °C(Predicted)

Density :

1.42±0.1 g/cm3(Predicted)

storage temp. :

Hygroscopic, -20°C Freezer, Under inert atmosphere

solubility :

Chloroform (Slightly), Ethyl Acetate (Slightly)

form :

Solid

appearance:

white crystals or powder

pka:

6.05±0.40(Predicted)

color :

White to Off-White

Stability::

Hygroscopic

InChI:

InChI=1S/C21H19FN6O2/c1-11-15-7-13(22)4-5-14(15)21(29)27(2)10-16-19(17(8-23)28(3)26-16)12-6-18(30-11)20(24)25-9-12/h4-7,9,11H,10H2,1-3H3,(H2,24,25)/t11-/m1/s1

InChIKey:

IIXWYSCJSQVBQM-LLVKDONJSA-N

SMILES:

[C@@H]1(C)C2=CC(F)=CC=C2C(=O)N(C)CC2=NN(C)C(C#N)=C2C2C=C(C(N)=NC=2)O1