COMPUTED DESCRIPTORS
Molecular Weight | 532.6 g/mol |
---|---|
XLogP3 | 1.1 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 9 |
Rotatable Bond Count | 14 |
Exact Mass | 532.19917055 g/mol |
Monoisotopic Mass | 532.19917055 g/mol |
Topological Polar Surface Area | 177 Ų |
Heavy Atom Count | 37 |
Formal Charge | 0 |
Complexity | 825 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 4 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Oprozomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, Waldenstrom Macroglobulinemia, Advanced Hepatocellular Carcinoma, and Advanced Non-Central Nervous System (CNS) Malignancies.