CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid; [Merck Index] |
|---|---|
| Color/Form | COLORLESS OR ALMOST COLORLESS IF CONTAINING NOT MORE THAN 100 USP UNITS/ML; STRAW-COLORED IF CONTAINING 500 UNITS |
| Solubility | READILY SOL IN DILUTE ACIDS; SOL IN WATER |
| Stability/Shelf Life | SHOULD BE STORED AT 2 TO 8 °C & SHOULD NOT BE SUBJECTED TO FREEZING OR EXTREMES IN TEMP |
| pH | 2.5-3.5 |
| Other Experimental Properties | CONTAINS 0.1 TO 0.25% (WT/VOL) OF EITHER PHENOL OR CRESOL & 1.4-1.8% (WT/VOL) OF GLYCERIN |
| Chemical Classes | Biological Agents -> Proteins |
COMPUTED DESCRIPTORS
| Molecular Weight | 5794 g/mol |
|---|---|
| XLogP3 | -12.8 |
| Hydrogen Bond Donor Count | 78 |
| Hydrogen Bond Acceptor Count | 89 |
| Rotatable Bond Count | 178 |
| Exact Mass | 5791.6287098 g/mol |
| Monoisotopic Mass | 5789.6220002 g/mol |
| Topological Polar Surface Area | 2450 Ų |
| Heavy Atom Count | 404 |
| Formal Charge | 0 |
| Complexity | 14600 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 52 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Insulin is a pancreatic hormone that plays an essential role in regulation of blood glucose as well as lipid and carbohydrate metabolism. Both natural and recombinant forms of insulin are used therapeutically to treat type 1 diabetes. While insulin itself is not hepatotoxic and has not been linked to serum enzyme elevations or instances of clinically apparent liver injury, high doses including overdoses of insulin and glucose can result in hepatic glycogenosis and serum aminotransferase elevations.