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89750-14-1

89750-14-1 structural image
Product Name: glucagon-like peptide 1
Formula: C149H226N40O45
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COMPUTED DESCRIPTORS

Molecular Weight 3297.6 g/mol
XLogP3 -14.2
Hydrogen Bond Donor Count 49
Hydrogen Bond Acceptor Count 50
Rotatable Bond Count 109
Exact Mass 3296.6659301 g/mol
Monoisotopic Mass 3295.6625752 g/mol
Topological Polar Surface Area 1390 Ų
Heavy Atom Count 234
Formal Charge 0
Complexity 7660
Isotope Atom Count 0
Defined Atom Stereocenter Count 30
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

A peptide of 36 or 37 amino acids that is derived from PROGLUCAGON and mainly produced by the INTESTINAL L CELLS. GLP-1(1-37 or 1-36) is further N-terminally truncated resulting in GLP-1(7-37) or GLP-1-(7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent INSULIN release, suppress GLUCAGON release and gastric emptying, lower BLOOD GLUCOSE, and reduce food intake.