COMPUTED DESCRIPTORS
| Molecular Weight | 209.21 g/mol |
|---|---|
| XLogP3 | -1.1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 4 |
| Exact Mass | 209.09127461 g/mol |
| Monoisotopic Mass | 209.09127461 g/mol |
| Topological Polar Surface Area | 99.1 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 206 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Desciclovir is a prodrug of acyclovir with activity against viruses in the herpesvirus family. Desciclovir is absorbed from the gastrointestinal tract and is converted to acyclovir by xanthine oxidase. Acyclovir is further converted to cyclovir triphosphate by viral thymidine kinase and competitively inhibits viral DNA polymerase by incorporating into the growing viral DNA chain and terminating further polymerization.