83905-01-5
Product Name:
Azithromycin
Formula:
C38H72N2O12
Synonyms:
N-Methyl-11-aza-10-deoxo-10-dihydroerythromycin A;Azithromycin;Azithromycin dihydrate;CP 62,993;CP-62993
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Color/Form | Amorphous solid |
| Melting Point | 126 |
| Solubility | soluble in ethanol and DSMO, minimally soluble in water |
| LogP | 3.03 |
| Optical Rotation | Specific optical rotation: -37 °C at 20 °C/D (c = 1 on CHCl3) |
| Ionization Efficiency | Positive |
| Dissociation Constants | 8.5 |
| Collision Cross Section | 263.5 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Health Hazard GHS08 |
| GHS Hazard Statements |
H317:Sensitisation, Skin H334:Sensitisation, respiratory |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P342+P311:IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician. |
COMPUTED DESCRIPTORS
| Molecular Weight | 749.0 g/mol |
|---|---|
| XLogP3 | 4 |
| Hydrogen Bond Donor Count | 5 |
| Hydrogen Bond Acceptor Count | 14 |
| Rotatable Bond Count | 7 |
| Exact Mass | 748.50852574 g/mol |
| Monoisotopic Mass | 748.50852574 g/mol |
| Topological Polar Surface Area | 180 Ų |
| Heavy Atom Count | 52 |
| Formal Charge | 0 |
| Complexity | 1150 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 18 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Azithromycin is a macrolide antibiotic useful for the treatment of bacterial infections. It has a role as an antibacterial drug, an environmental contaminant and a xenobiotic.