SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H301:Acute toxicity,oral H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
COMPUTED DESCRIPTORS
| Molecular Weight | 148.54 g/mol |
|---|---|
| XLogP3 | 1.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Exact Mass | 147.9927217 g/mol |
| Monoisotopic Mass | 147.9927217 g/mol |
| Topological Polar Surface Area | 35.5 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 173 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
Description
4-Chloromethyl-5-methyl-1,3-dioxol-2-one is an impurity that can be found in the reaction mixture of medoxomil. It is a genotoxic impurity and can cause damage to DNA.
RELATED SUPPLIERS
KARPSCHEM LABORATORIES PVT. LTD.
1Y
product:80841-78-7 Olmesartan Medoxomil Impurity 5
(5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl Chloride; 4- Chloromethyl-5-methyl-2-oxo-1,3-dioxole 96%
Chemeca Drugs Private Limited (Vegesna Laboratories Pvt Ltd)
1Y
product:4-Chloromethyl-5-methyl-[1,3]dioxol-2-one 98%