80012-44-8
Product Name:
Epinastine hydrochloride
Formula:
C16H16ClN3
Synonyms:
9,13b-Dihydro-1H-dibenz[cf]imidazo[1,5-a]azepine hydrochloride;WAL-801Cl
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COMPUTED DESCRIPTORS
| Molecular Weight | 285.77 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 285.1032752 g/mol |
| Monoisotopic Mass | 285.1032752 g/mol |
| Topological Polar Surface Area | 41.6 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 378 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Epinastine Hydrochloride is an histamine H1 receptor antagonist without sedative activity. Epinastine hydrochloride blocks the histamine H1 receptor and inhibits the release of histamine from mast cells. This prevents the typical allergic symptoms that are caused by histamine activity on capillaries, skin, mucous membranes, and on gastrointestinal and bronchial smooth muscles. Typical histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Epinastine also has affinity for the histamine H2, 5-HT2, and the alpha-1, alpha-2 adrenergic receptors.
RELATED SUPPLIERS
Rivashaa Agrotech Biopharma Pvt. Ltd.
1Y
product:80012-44-8 / 108929-04-0 Epinastine hydrochloride 98%