78628-80-5
Product Name:
Terbinafine Hydrochloride
Formula:
C21H26ClN
Synonyms:
trans-N-(6,6-Dimethyl-2-hepten-4-ylyl)-N-methyl-1-naphthylmethylamine hydrochloride
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SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Environment GHS09 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation H410:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P273:Avoid release to the environment. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
PRODUCT INTRODUCTION
Description
Terbinafine hydrochloride, commercially known as Lamisil, is classified as a synthetic allylamine antifungal agent. Its distinctive feature lies in its high lipophilicity, which results in a tendency to accumulate within skin, nails, and fatty tissues. Functionally, it operates similarly to other allylamines by impeding ergosterol synthesis. This inhibition primarily occurs through the suppression of fungal squalene monooxygenase, also known as squalene epoxidase, an essential enzyme involved in the fungal cell wall synthesis pathway.
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