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68038-70-0

Product Name: Bacillus subtilis
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CHEMICAL AND PHYSICAL PROPERTIES

Color/Form Dry off-white to tan solid
Solubility Insoluble in water
Density 26-29 lb/cu ft
Other Experimental Properties Stable in dry, ambient conditions for at least 2 yrs
Chemical Classes UVCB

COMPUTED DESCRIPTORS

Molecular Weight 1488.1 g/mol
Hydrogen Bond Donor Count 16
Hydrogen Bond Acceptor Count 21
Rotatable Bond Count 31
Exact Mass 1485.678083 g/mol
Monoisotopic Mass 1485.678083 g/mol
Topological Polar Surface Area 552 Ų
Heavy Atom Count 101
Formal Charge 0
Complexity 2950
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 16
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Bacitracin Zinc is the zinc salt form of bacitracin, a complex of cyclic polypeptide antibiotics, mainly bacitracin A, produced by spore-forming organisms belonging to the licheniformin group of the Bacillus subtilis with antibacterial activity. Bacitracin zinc binds to C55-isoprenyl pyrophosphate, a biphosphate lipid transport molecule that carries the building blocks of the peptidoglycan bacterial cell wall, thereby interfering with the enzymatic dephosphorylation of the C55-isoprenyl pyrophosphate and preventing peptidoglycan synthesis which leads to cell lysis.

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