CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Boiling Point | 224.1ºC at 760 mmHg |
| Melting Point | 223-226 °C |
| Solubility | Freely soluble |
| LogP | -2.6 |
| Stability/Shelf Life | Stable under recommended storage conditions. /Metformin hydrochloride/ |
| Decomposition | Hazardous decomposition products formed under fire conditions - Carbon oxides, nitrogen oxides (NOx), hydrogen chloride gas. /Metformin hydrochloride/ |
| Ionization Efficiency | Positive |
| Dissociation Constants | 12.4 |
| Other Experimental Properties | MW: 165.63. Prisms from water, MP 232 °C; crystals from propanol, MP 218-220 °C. Freely soluble in water; slightly soluble in alcohol. Practically insoluble in ether, chloroform, acetone, methylene chloride. /Metformin hydrochloride/ |
COMPUTED DESCRIPTORS
| Molecular Weight | 129.16 g/mol |
|---|---|
| XLogP3 | -1.3 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 2 |
| Exact Mass | 129.10144537 g/mol |
| Monoisotopic Mass | 129.10144537 g/mol |
| Topological Polar Surface Area | 91.5 Ų |
| Heavy Atom Count | 9 |
| Formal Charge | 0 |
| Complexity | 132 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Metformin is a member of the class of guanidines that is biguanide the carrying two methyl substituents at position 1. It has a role as a hypoglycemic agent, a xenobiotic, an environmental contaminant and a geroprotector. It is functionally related to a biguanide. It is a conjugate base of a metformin(1+).