62253-63-8
Product Name:
Epidermal Growth Factor
Formula:
C270H401N73O83S7
Synonyms:
EGF;EGP;Epidermal Growth Factor human;Epithelial cell surface antigen;Epithelial glycoprotein
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COMPUTED DESCRIPTORS
| Molecular Weight | 6222 g/mol |
|---|---|
| XLogP3 | -17.3 |
| Hydrogen Bond Donor Count | 94 |
| Hydrogen Bond Acceptor Count | 98 |
| Rotatable Bond Count | 203 |
| Exact Mass | 6219.7513614 g/mol |
| Monoisotopic Mass | 6217.7446517 g/mol |
| Topological Polar Surface Area | 2550 Ų |
| Heavy Atom Count | 433 |
| Formal Charge | 0 |
| Complexity | 15800 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 51 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Nepidermin is a recombinant form of the naturally-occurring polypeptide human epidermal growth factor with potential epithelial regenerative and cytoprotective activities. Upon topical application, recombinant human epidermal growth factor (rhEGF) may stimulate epithelial proliferation, differentiation and migration, which may result in the acceleration of epithelial regeneration and wound healing. In addition, rhEGF may attenuate epithelial cytotoxicities related to chemotherapy and/or radiotherapy.