CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
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Solubility | Soluble |
LogP | -2.1 |
COMPUTED DESCRIPTORS
Molecular Weight | 525.6 g/mol |
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XLogP3 | -2.4 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 13 |
Rotatable Bond Count | 10 |
Exact Mass | 525.10351377 g/mol |
Monoisotopic Mass | 525.10351377 g/mol |
Topological Polar Surface Area | 251 Ų |
Heavy Atom Count | 34 |
Formal Charge | 0 |
Complexity | 848 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 2 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Cefotiam is a cephalosporin with ({1-[2-(dimethylamino)ethyl]-1H-tetrazol-5-yl}sulfanyl)methyl and (2-amino-1,3-thiazol-4-yl)acetamido substituents at positions 3 and 7, respectively, of the cephem skeleton. A third generation beta-lactam cephalosporin antibiotic, it is active against a broad spectrum of both Gram positive and Gram negative bacteria. It has a role as an antibacterial drug. It is a cephalosporin, a semisynthetic derivative and a beta-lactam antibiotic allergen.