60643-86-9
Product Name:
VIGABATRIN
Formula:
C6H11NO2
Synonyms:
(±)-γ-Vinyl-GABA;(±)-4-Aminohexenoic acid;(±)-Vigabatrin;(R,S)-4-Amino-5-hexenoic acid
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
---|---|
Color/Form | Crystals from acetone/water |
Melting Point | 171-176C |
Solubility | 55.1 mg/mL |
LogP | -1.96 |
Stability/Shelf Life | Stable under recommended storage conditions. |
pH | pH = 6.9 (1% aqueous solution) |
Dissociation Constants | 4 and 9.7 |
Other Experimental Properties | A racemate consisting of two enantiomers |
SAFETY INFORMATION
Signal word | Danger |
---|---|
Pictogram(s) |
Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 |
GHS Hazard Statements |
H225:Flammable liquids H370:Specific target organ toxicity, single exposure |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P311:Call a POISON CENTER or doctor/physician. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
COMPUTED DESCRIPTORS
Molecular Weight | 129.16 g/mol |
---|---|
XLogP3 | -2.2 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 3 |
Rotatable Bond Count | 4 |
Exact Mass | 129.078978594 g/mol |
Monoisotopic Mass | 129.078978594 g/mol |
Topological Polar Surface Area | 63.3 Ų |
Heavy Atom Count | 9 |
Formal Charge | 0 |
Complexity | 112 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 1 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Vigabatrin is a gamma-amino acid having a gamma-vinyl GABA structure. It is an irreversible inhibitor of gamma-aminobutyric 664 acid transaminase It has a role as an anticonvulsant and an EC 2.6.1.19 (4-aminobutyrate--2-oxoglutarate transaminase) inhibitor.