604-75-1
Product Name:
OXAZEPAM
Formula:
C15H11ClN2O2
Synonyms:
7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-1,4(2H)-benzodiazepin-2-one
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Oxazepam appears as odorless creamy-white to pale-yellow powder or white crystalline solid. Bitter taste. pH (2% aqueous suspension) 4.8-7. (NTP, 1992) |
|---|---|
| Color/Form | Crystals from alcohol |
| Odor | PRACTICALLY ODORLESS |
| Taste | BITTER |
| Melting Point | 401 to 403 °F (NTP, 1992) |
| Solubility | less than 1 mg/mL at 66 °F (NTP, 1992) |
| Vapor Pressure | 4.2X10-12 mm Hg at 25 °C /Estimated/ |
| LogP | 2.24 |
| Henry's Law Constant | Henry's Law constant = 5.5X10-10 atm-cu m/mole at 25 °C /Estimated/ |
| Stability/Shelf Life | STABLE IN LIGHT |
| pH | BETWEEN 4.8 AND 7.0 (1 IN 50 SUSPENSION) |
| Dissociation Constants | pKa1: 1.55 (-C=N-); pKa2: 10.9 (-OH) /Estimated/ |
| Collision Cross Section | 162.3 Ų [M+H]+ [CCS Type: TW, Method: Major Mix IMS/Tof Calibration Kit (Waters)] |
| Kovats Retention Index | 2323 2291 2300 2293 2294 2293 2320 2350 2350 2374 2331 2380 2380 2380 2380 2336 2374 2327.6 2317.7 2336 2310 2336 2314 2354 2293 2294 2300 2335 2300 2325 2336 2370 2373 2318 2318 |
| Other Experimental Properties | NONHYGROSCOPIC |
SAFETY INFORMATION
| Signal word | Warning |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H336:Specific target organ toxicity,single exposure; Narcotic effects H351:Carcinogenicity |
| Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P308+P313:IF exposed or concerned: Get medical advice/attention. |
COMPUTED DESCRIPTORS
| Molecular Weight | 286.71 g/mol |
|---|---|
| XLogP3 | 2.2 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Exact Mass | 286.0509053 g/mol |
| Monoisotopic Mass | 286.0509053 g/mol |
| Topological Polar Surface Area | 61.7 Ų |
| Heavy Atom Count | 20 |
| Formal Charge | 0 |
| Complexity | 407 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Oxazepam appears as odorless creamy-white to pale-yellow powder or white crystalline solid. Bitter taste. pH (2% aqueous suspension) 4.8-7. (NTP, 1992)