594839-88-0
Product Name:
2-(3,5-Dichlorophenyl)-6-benzoxazole carboxylic acid
Formula:
C14H7Cl2NO3
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
Solubility | >50mg/mL |
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COMPUTED DESCRIPTORS
Molecular Weight | 308.1 g/mol |
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XLogP3 | 4.2 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 4 |
Rotatable Bond Count | 2 |
Exact Mass | 306.9802985 g/mol |
Monoisotopic Mass | 306.9802985 g/mol |
Topological Polar Surface Area | 63.3 Ų |
Heavy Atom Count | 20 |
Formal Charge | 0 |
Complexity | 371 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Tafamidis is a member of the class of 1,3-benzoxazoles that is 1,3-benzoxazole-6-carboxylic acid in which the hydrogen at position 2 is replaced by a 3,5-dichlorophenyl group. Used (as its meglumine salt) for the amelioration of transthyretin-related hereditary amyloidosis. It has a role as a central nervous system drug. It is a member of 1,3-benzoxazoles, a monocarboxylic acid and a dichlorobenzene. It is a conjugate acid of a tafamidis(1-).