CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | Solid |
|---|---|
| Color/Form | Hygroscopic powder |
| Odor | Odorless or nearly so |
| Taste | Slightly bitter taste |
| Boiling Point | 872.9∓75.0°C at 760 mmHg |
| Melting Point | MW: 1457.383. Powder. MP: aproximately 230 °C /Streptomycin sulfate; 3810-74-0/ |
| Solubility | White to light gray or pale buff powder; faint amine-like odor; solubility in mg/mL at about 28 °C: water greater than 20; methanol 0.85; ethanol 0.30; isopropanol 0.01; petroleum ether 0.015; carbon tetrachloride 0.035; ether 0.035, Practically insoluble in chloroform. /Streptomycin sesquisulfate/ |
| LogP | -2.53 |
| Stability/Shelf Life | Quite stable but very hygroscopic. |
| Optical Rotation | Very hygroscopic, decomposes at about 200 °C. Specific optical rotation: -76 deg at 25 °C/D /Streptomycin trihydrochloride-calcium chloride double salt/ |
| Decomposition | When heated to decomposition it emits toxic fumes of /nitrogen oxides/. |
| pH | Highly polar organic base |
| Collision Cross Section | 231 Ų [M+H]+ [CCS Type: TW, Method: calibrated with Waters Major Mix] |
| Other Experimental Properties | Stable at <2pH<9 but unstable in strong acids and alkalis |
| Chemical Classes | Other Uses -> Pharmaceuticals |
COMPUTED DESCRIPTORS
| Molecular Weight | 581.6 g/mol |
|---|---|
| XLogP3 | -8 |
| Hydrogen Bond Donor Count | 12 |
| Hydrogen Bond Acceptor Count | 15 |
| Rotatable Bond Count | 9 |
| Exact Mass | 581.26566970 g/mol |
| Monoisotopic Mass | 581.26566970 g/mol |
| Topological Polar Surface Area | 336 Ų |
| Heavy Atom Count | 40 |
| Formal Charge | 0 |
| Complexity | 940 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 15 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Streptomycin is a amino cyclitol glycoside that consists of streptidine having a disaccharyl moiety attached at the 4-position. The parent of the streptomycin class It has a role as an antimicrobial agent, an antimicrobial drug, an antibacterial drug, a protein synthesis inhibitor, a bacterial metabolite and an antifungal agrochemical. It is an antibiotic antifungal drug, an antibiotic fungicide and a member of streptomycins. It is functionally related to a streptidine. It is a conjugate base of a streptomycin(3+).