56390-09-1
Product Name:
Epirubicin hydrochloride
Formula:
C27H30ClNO11
Synonyms:
4′-Epidoxorubicin hydrochloride;Epidoxorubicin hydrochloride
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Collision Cross Section | 225.2 Ų [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards] |
|---|
SAFETY INFORMATION
| Signal word | Danger |
|---|---|
| Pictogram(s) |
 Exclamation Mark Irritant GHS07  Health Hazard GHS08 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H340:Germ cell mutagenicity H350:Carcinogenicity H360:Reproductive toxicity |
| Precautionary Statement Codes |
P201:Obtain special instructions before use. P308+P313:IF exposed or concerned: Get medical advice/attention. |
COMPUTED DESCRIPTORS
| Molecular Weight | 580.0 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 7 |
| Hydrogen Bond Acceptor Count | 12 |
| Rotatable Bond Count | 5 |
| Exact Mass | 579.1507385 g/mol |
| Monoisotopic Mass | 579.1507385 g/mol |
| Topological Polar Surface Area | 206 Ų |
| Heavy Atom Count | 40 |
| Formal Charge | 0 |
| Complexity | 977 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 6 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Epirubicin Hydrochloride is the hydrochloride salt of the 4'-epi-isomer of the anthracycline antineoplastic antibiotic doxorubicin. Epirubicin intercalates into DNA and inhibits topoisomerase II, thereby inhibiting DNA replication and ultimately, interfering with RNA and protein synthesis. This agent also produces toxic free-radical intermediates and interacts with cell membrane lipids causing lipid peroxidation.
RELATED SUPPLIERS
Archerchem Healthcare Pvt., Ltd. (part of Archerchem Group)
Maharashtra
product:Epirubicin hydrochloride