496868-77-0
Product Name:
(2E)-3-(4'-Hydroxy-3'-tricyclo[3.3.1.13,7]dec-1-yl[1,1'-biphenyl]-4-yl)-2-propenoic acid
Formula:
C25H26O3
Inquiry
COMPUTED DESCRIPTORS
Molecular Weight | 374.5 g/mol |
---|---|
XLogP3 | 6.5 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 3 |
Rotatable Bond Count | 4 |
Exact Mass | 374.18819469 g/mol |
Monoisotopic Mass | 374.18819469 g/mol |
Topological Polar Surface Area | 57.5 Ų |
Heavy Atom Count | 28 |
Formal Charge | 0 |
Complexity | 574 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 1 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Adarotene is a synthetic, phenolic hydroxyl retinoid with proapoptotic activity. As an atypical retinoid, adarotene has the ability to induce apoptosis which is independent of retinoid receptor signaling.