SAFETY INFORMATION
Signal word | Warning |
---|---|
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up. |
COMPUTED DESCRIPTORS
Molecular Weight | 232.66 g/mol |
---|---|
XLogP3 | 3.7 |
Hydrogen Bond Donor Count | 1 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 2 |
Exact Mass | 232.0291072 g/mol |
Monoisotopic Mass | 232.0291072 g/mol |
Topological Polar Surface Area | 37.3 Ų |
Heavy Atom Count | 16 |
Formal Charge | 0 |
Complexity | 238 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
Description
4-Chloro-4'-hydroxybenzophenone is a pharmaceutical intermediate compound used in the preparation of Fenofibrate. Fenofibrate is used to reduce the levels of fatty substances such as cholesterol and triglycerides in the blood and to increase the blood levels of HDL (high-density lipoprotein; a fatty substance that reduces the risk of heart disease). levels of HDL (high-density lipoprotein; a fatty substance that reduces the risk of heart disease). It is approved by the FDA for the treatment of patients with hypertriglyceridemia, primary hypercholesterolaemia or mixed dyslipidaemia.