CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
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Melting Point | 287-289 °C |
Solubility | >29.1 [ug/mL] (The mean of the results at pH 7.4) |
LogP | 0.33 |
COMPUTED DESCRIPTORS
Molecular Weight | 194.19 g/mol |
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XLogP3 | 0.3 |
Hydrogen Bond Donor Count | 2 |
Hydrogen Bond Acceptor Count | 3 |
Rotatable Bond Count | 2 |
Exact Mass | 194.08037557 g/mol |
Monoisotopic Mass | 194.08037557 g/mol |
Topological Polar Surface Area | 78.1 Ų |
Heavy Atom Count | 14 |
Formal Charge | 0 |
Complexity | 268 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Enprofylline is xanthine bearing a propyl substituent at position 3. A bronchodilator, it is used for the symptomatic treatment of asthma and chronic obstructive pulmonary disease, and in the management of cerebrovascular insufficiency, sickle cell disease, and diabetic neuropathy. It has a role as a non-steroidal anti-inflammatory drug, a bronchodilator agent, an anti-asthmatic drug and an anti-arrhythmia drug.