37326-33-3
Product Name:
Hyaluronidase
Formula:
NULL
Synonyms:
Hyaluronate 4-glycanohydrolase;Hyaluronidase - CAS 37326-33-3 - Calbiochem;Hyaluronidase, Bovine Testes;Hyaluronidase, Ovine Testes;Hyaluronoglucosaminidase
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CHEMICAL AND PHYSICAL PROPERTIES
| Physical Description | White cake; [Sigma-Aldrich MSDS] |
|---|---|
| Chemical Classes | Biological Agents -> Enzymes |
COMPUTED DESCRIPTORS
| Molecular Weight | 354.3 g/mol |
|---|---|
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 6 |
| Exact Mass | 353.09904 g/mol |
| Monoisotopic Mass | 353.09904 g/mol |
| Topological Polar Surface Area | 40.5 Ų |
| Heavy Atom Count | 21 |
| Formal Charge | 0 |
| Complexity | 375 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Hyaluronidase is an enzyme used to improve the absorption and dispersion of parenterally administered fluids, drugs, and contrast agents. The action of hyaluronidase was first described in 1936, and named in 1939. Early research into hyaluronidase identified it as a "spreading factor" which allowed for increased permeability of the connective tissue. Hyaluronidase has been used in surgical settings for at least the past 60 years to improve the diffusion of local anesthetics. Hyaluronidase was first used in prescription products in the United States on 5 May 2004.