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34273-12-6

34273-12-6 structural image
Product Name: H-ASP-ARG-VAL-TYR-ILE-HIS-PRO-PHE-HIS-OH
Formula: C56H78N16O13
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COMPUTED DESCRIPTORS

Molecular Weight 1183.3 g/mol
XLogP3 -2.2
Hydrogen Bond Donor Count 15
Hydrogen Bond Acceptor Count 17
Rotatable Bond Count 33
Exact Mass 1182.59342661 g/mol
Monoisotopic Mass 1182.59342661 g/mol
Topological Polar Surface Area 467 Ų
Heavy Atom Count 85
Formal Charge 0
Complexity 2300
Isotope Atom Count 0
Defined Atom Stereocenter Count 10
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Angiotensin (1-9) is a nine amino acid peptide which is formed when angiotensin converting enzyme 2 (ACE2) hydrolyzes the carboxy terminal leucine from angiotensin I. It is a anti-cardiac hypertrophy agent. It has a role as a human metabolite, a rat metabolite, an antihypertensive agent and a cardioprotective agent. It is a tautomer of an angiotensin (1-9) dizwitterion.