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27761-19-9

27761-19-9 structural image
Product Name: Cysteamine bitartrate
Formula: C6H13NO6S
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COMPUTED DESCRIPTORS

Molecular Weight 227.24 g/mol
Hydrogen Bond Donor Count 6
Hydrogen Bond Acceptor Count 8
Rotatable Bond Count 4
Exact Mass 227.04635831 g/mol
Monoisotopic Mass 227.04635831 g/mol
Topological Polar Surface Area 142 Ų
Heavy Atom Count 14
Formal Charge 0
Complexity 144
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 2
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Cysteamine Bitartrate is an aminothiol salt used in the treatment of nephropathic cystinosis. Cysteamine bitartrate enters the cell and reacts with cystine producing cysteine and cysteine-cysteamine mixed disulfide compound, both of which, unlike cystine, can pass through the lysosomal membrane. This prevents the accumulation of cystine crystals in the lysosomes of patients with cystinosis, which can cause considerable damage and eventual destruction of the cells, particularly in the kidneys. (NCI05)

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