25876-10-2
Product Name:
(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-[(1R)-1-methylaminoethyl]oxan-2-yl]oxy-2-hydroxy-cyclohexyl]oxy-5-methyl-4-methylamino-oxane-3,5-diol
Formula:
C21H43N5O7
Inquiry
CHEMICAL AND PHYSICAL PROPERTIES
| Color/Form | White amorphous powder |
|---|---|
| Melting Point | 102-108 °C |
| Solubility | Freely soluble in water |
| Stability/Shelf Life | Stable in light, air, and heat /Gentamycin sulfate/ |
| Optical Rotation | Specific optical rotation: +146 deg at 25 °C/D |
| Decomposition | When heated to decomposition it emits acrid smoke and irritating fumes. |
| Collision Cross Section | 214.5 Ų [M+H]+ [CCS Type: TW, Method: calibrated with Waters Major Mix] |
| Other Experimental Properties | MP: 94-100 °C; Specific optical rotation: +158 deg at 25 °C/D /Gentamicin C1/ |
| Chemical Classes | Other Uses -> Pharmaceuticals |
COMPUTED DESCRIPTORS
| Molecular Weight | 477.6 g/mol |
|---|---|
| XLogP3 | -4.1 |
| Hydrogen Bond Donor Count | 8 |
| Hydrogen Bond Acceptor Count | 12 |
| Rotatable Bond Count | 7 |
| Exact Mass | 477.31624873 g/mol |
| Monoisotopic Mass | 477.31624873 g/mol |
| Topological Polar Surface Area | 200 Ų |
| Heavy Atom Count | 33 |
| Formal Charge | 0 |
| Complexity | 636 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 13 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 1 |
| Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Gentamicin is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of several infections caused by certain types of bacteria, such as meningitis, infection of the blood, and serious urinary tract infections.