CHEMICAL AND PHYSICAL PROPERTIES
Physical Description | Solid |
---|---|
Solubility | 8.53e-02 g/L |
LogP | 2.1 |
COMPUTED DESCRIPTORS
Molecular Weight | 410.5 g/mol |
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XLogP3 | 1.9 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 7 |
Rotatable Bond Count | 2 |
Exact Mass | 410.19048031 g/mol |
Monoisotopic Mass | 410.19048031 g/mol |
Topological Polar Surface Area | 94.8 Ų |
Heavy Atom Count | 29 |
Formal Charge | 0 |
Complexity | 839 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 9 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
Diflorasone is the 16beta-analogue of flumethasone. It is used as the 17,21-diacetate as a topical anti-inflammatory and antipruritic in the treatment of various skin disorders. It has a role as an anti-inflammatory drug. It is an 11beta-hydroxy steroid, a 20-oxo steroid, a 17alpha-hydroxy steroid, a fluorinated steroid, a glucocorticoid, a 21-hydroxy steroid, a 3-oxo-Delta(1),Delta(4)-steroid, a primary alpha-hydroxy ketone and a tertiary alpha-hydroxy ketone. It derives from a hydride of a pregnane.