2398-96-1

Product Name: Tolnaftate

Formula: C19H17NOS

Synonyms: Methyl-(3-methylphenyl)carbamothioic acid O-2-naphthyl ester;Tolnaftate

Inquiry

CHEMICAL AND PHYSICAL PROPERTIES SAFETY INFORMATION COMPUTED DESCRIPTORS PRODUCT INTRODUCTION RELATED SUPPLIERS

CHEMICAL AND PHYSICAL PROPERTIES

Physical Description	Crystals or white powder. (NTP, 1992)
Melting Point	230.9 to 232.7 °F (NTP, 1992)
Solubility	less than 1 mg/mL at 72 °F (NTP, 1992)
LogP	5.1
Collision Cross Section	173.6 Å² [M+H]+ [CCS Type: TW, Method: calibrated with polyalanine and drug standards]

SAFETY INFORMATION

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

COMPUTED DESCRIPTORS

Molecular Weight	307.4 g/mol
XLogP3	5.5
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	3
Exact Mass	307.10308534 g/mol
Monoisotopic Mass	307.10308534 g/mol
Topological Polar Surface Area	44.6 Å²
Heavy Atom Count	22
Formal Charge	0
Complexity	386
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

PRODUCT INTRODUCTION

description

Tolnaftate belongs to the group of medicines called antifungals. It is a crystals or white powder and used to treat some types of fungus infections. It may also be used together with medicines taken by mouth for fungus infections.