223387-75-5
Product Name:
FG 2216
Formula:
C12H9ClN2O4
Synonyms:
[[(1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl]amino]acetic acid;IOX 3;N-[(1-Chloro-4-hydroxy-3-isoquinolinyl)carbonyl]glycine;
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SAFETY INFORMATION
Signal word | Warning |
---|---|
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
Precautionary Statement Codes |
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
COMPUTED DESCRIPTORS
Molecular Weight | 280.66 g/mol |
---|---|
XLogP3 | 2.5 |
Hydrogen Bond Donor Count | 3 |
Hydrogen Bond Acceptor Count | 5 |
Rotatable Bond Count | 3 |
Exact Mass | 280.0250845 g/mol |
Monoisotopic Mass | 280.0250845 g/mol |
Topological Polar Surface Area | 99.5 Ų |
Heavy Atom Count | 19 |
Formal Charge | 0 |
Complexity | 366 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently-Bonded Unit Count | 1 |
Compound Is Canonicalized | Yes |
PRODUCT INTRODUCTION
description
A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.