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223387-75-5

223387-75-5 structural image
Product Name: FG 2216
Formula: C12H9ClN2O4
Synonyms: [[(1-Chloro-4-hydroxyisoquinolin-3-yl)carbonyl]amino]acetic acid;IOX 3;N-[(1-Chloro-4-hydroxy-3-isoquinolinyl)carbonyl]glycine;
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SAFETY INFORMATION

Signal word Warning
Pictogram(s)

Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

COMPUTED DESCRIPTORS

Molecular Weight 280.66 g/mol
XLogP3 2.5
Hydrogen Bond Donor Count 3
Hydrogen Bond Acceptor Count 5
Rotatable Bond Count 3
Exact Mass 280.0250845 g/mol
Monoisotopic Mass 280.0250845 g/mol
Topological Polar Surface Area 99.5 Ų
Heavy Atom Count 19
Formal Charge 0
Complexity 366
Isotope Atom Count 0
Defined Atom Stereocenter Count 0
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

A orally active prolyl-hydroxylase inhibitor which can stabilize hypoxia-inducible transcription factor independent of oxygen availability.