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218949-48-5

Product Name: Tesamorelin
Formula: C221H366N72O67S
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COMPUTED DESCRIPTORS

Molecular Weight 5136 g/mol
XLogP3 -23.3
Hydrogen Bond Donor Count 83
Hydrogen Bond Acceptor Count 76
Rotatable Bond Count 187
Exact Mass 5134.7233503 g/mol
Monoisotopic Mass 5132.7166406 g/mol
Topological Polar Surface Area 2360 Ų
Heavy Atom Count 361
Formal Charge 0
Complexity 12800
Isotope Atom Count 0
Defined Atom Stereocenter Count 44
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 1
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 1
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Tesamorelin is a synthetic growth hormone releasing hormone analogue used in the treatment of visceral adiposity in human immunodeficiency virus (HIV) infected patients with lipodystrophy. Tesamorelin is given subcutaneously and has major effects on glucose and lipid metabolism, but has not been linked to serum aminotransferase elevations during therapy or to instances of clinically apparent acute liver injury.