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217797-14-3

217797-14-3 structural image
Product Name: paroxetine Mesylate
Formula: C20H24FNO6S
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COMPUTED DESCRIPTORS

Molecular Weight 425.5 g/mol
Hydrogen Bond Donor Count 2
Hydrogen Bond Acceptor Count 8
Rotatable Bond Count 4
Exact Mass 425.13083682 g/mol
Monoisotopic Mass 425.13083682 g/mol
Topological Polar Surface Area 103 Ų
Heavy Atom Count 29
Formal Charge 0
Complexity 495
Isotope Atom Count 0
Defined Atom Stereocenter Count 2
Undefined Atom Stereocenter Count 0
Defined Bond Stereocenter Count 0
Undefined Bond Stereocenter Count 0
Covalently-Bonded Unit Count 2
Compound Is Canonicalized Yes

PRODUCT INTRODUCTION

description

Paroxetine Mesylate is the mesylate salt form of paroxetine, a phenylpiperidine derivative and a selective serotonin reuptake inhibitor (SSRI) with antidepressant and anxiolytic properties. Paroxetine binds to the pre-synaptic serotonin transporter complex resulting in negative allosteric modulation of the complex, thereby blocking reuptake of serotonin by the pre-synaptic transporter. Inhibition of serotonin recycling enhances serotonergic function through serotonin accumulation in the synaptic cleft, which resulting in long-term desensitization and downregulation of 5HT1 (serotonin) receptors and leading to symptomatic relief of depressive illness.

RELATED SUPPLIERS

Enal Drugs Pvt Ltd

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product:Paroxetine mesylate 98%

Lavybens Pharma

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product:217797-14-3 98%
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